Category: Business News

Let’s Talk Shit

Let’s Talk Sh!t

Let’s Talk Shit Disease, Digestion & Fecal Transplants

Let’s Talk Sh!t is a humorous, easy to digest explanation of gastrointestinal disorders, their current treatments, as well as next generation hope for heart disease, obesity, autism, Alzheimer’s, and more. From constipation to cancer, research indicates that our unique microbiomes may be the basis for future advances in health and wellness.

Let’s Talk Sh!t examines the human microbiome—the  dynamic world of bacteria, fungus, and viruses that comprises more than 50% of our mortal selves.

Dr. Sabine Hazan and Dr. Thomas Borody, leaders in microbiome research, explore the reason therapies may not be working for many and why fecal transplants may be part of the solution. They also share nutritional tips to avoid illness, improve digestion, and support our own microbiomes.

About the Authors

Sabine Hazan

lets talk shit, Sabine Hazan

Sabine Hazan was the first of four children born to two government accountants in Morocco. In 1974 the family moved to Montreal, Canada to provide better education and greater opportunities. There, the Hazans raised their children with the ambition to match their potential—all became doctors.  

Throughout her life, Sabine’s peers questioned her dream to become a physician. But their challenges only fueled her ambitions. Even though her primary language was French, she enrolled in Concordia University, an English-speaking college.

Medical school admittance was difficult and more so for a woman. Sabine was asked: What if you become pregnant? What would you do if your child was sick and you also had a sick patient needing care? Whom would you choose? She wondered how many men were asked such questions.

She graduated from Dalhousie Medical School in Halifax, Nova Scotia. Curious about the American health care system, she chose to do her residency in Internal Medicine at Jackson Memorial Hospital, a notoriously demanding and rigorous county hospital in Miami. There, during the height of the HIV/AIDS crisis, she was under fire, learning to care for the most underserved patients who were desperately ill and dying. She fell further in love with medicine and with a fellow resident whom she married in 1993.

During her early medical career, she was keenly interested in gastroenterology. “It’s a man’s specialty,” she was told repeatedly. She would never be accepted. The naysayers again had the opposite effect and emboldened her resolve. In 1995, She became the first female Gastroenterology Fellow accepted at the University of Florida in Jacksonville. As a fellow, she discovered that she really enjoyed and excelled in clinical research, which led to awards from the university’s Dean for Research as well as recognition from the American College of Physicians. At the time, her primary research was in esophageal diseases, part of her work with her formidable mentor, Dr. Sami Achem. Her husband, Dr. Alon Steinberg, completed his Cardiology Fellowship at the same time and the couple had their first daughter in 1996.

Following her fellowship, Dr. Hazan returned to Montreal and opened a practice across the border in Upstate New York. Her enviable reputation grew quickly and due to socialized medicine in Canada, long wait lists for procedures like colonoscopies brought in many Canadian patients in need of gastroenterology care.

Just as Apple and Tesla were visionaries of technology, Dr. Hazan pursued innovation in medicine. Some perceived her as a threat. A perfectionist in her scientific approach and focused in her quest for excellence, the multi-tasking Hazan was never one for bureaucracy and red tape. She was reported to the medical board, cited for poor record keeping and required to take a course. The experience changed her. She became a warrior who vowed to extend her methodical approach in medical care to its documentation. In the ensuing years she emphasized extreme attention to detail, not just in her work product, but in her clinical research and records. She now embraces oversight from the Food and Drug Administration (FDA) and Independent Review Board (IRB). Her clinical trials are known for their validation and verification.

After the couple’s second daughter was born in 2004, Dr. Hazan rediscovered her passion for research and launched Ventura Clinical Trials. In 2005, she and her husband established respective patient practices in Ventura. Over the years, she attended several national GI conferences where she often met with her good friend and colleague, Dr. Neil Stollman, also a Gastroenterology Fellow in Miami during their residency years. Dr. Stollman had introduced her to the world of fecal microbiota transplant (FMT) and research by Dr. Thomas Borody since the late ‘90s.

Dr. Hazan started researching the use of FMT to treat patients with C. diff, which changed the trajectory of her career. It was Dr. Stollman’s explorations that inspired her to consider the human digestive tract as the body’s Garden of Eden. She later met Dr. Thomas Borody, the father of modern FMT. The meeting proved to be the beginning of a great collaborative relationship that continues to this day as they work together on advanced clinical research of the microbiome. 

After hundreds of clinical trials and treating thousands of patients, Dr. Hazan still faced persistent questions about life, death, health, illness, the gut, and how they were connected. Various curiosities, innovative concepts and ruminations kept her awake at night. Why did she crave McDonald’s when she was pregnant the first time? Why does her first daughter still love it? Alternatively, why does her youngest love vegetables, which Sabine craved often during her second pregnancy? Through research, she saw how dramatically the microbiome impacted human health, and she grew increasingly determined to understand.

Her curiosity led her to Dr. Sydney Finegold at UCLA. Dr. Finegold was certain of an association between bacteria, bowels, and behavior. He was especially sure of a connection between anaerobic bacteria and autism. If bacteria could contribute to autistic behavior, Dr. Hazan wondered if other tendencies, preferences, and characteristics could also be consequences of one’s microbiome.

Could she study the bacteria in human feces and isolate it for treatment? Could she continue trailblazing through an emerging science? When preliminary research of the microbiome led to fecal material in capsules, with venture capitalists controlling the stocks of sh!t, one could say she went rogue. Strongly opposed to a “one pill fits all” solution, she felt called to pioneer her own microbiome research at the clinical level. She was determined to develop valid reproducible data and to leverage that data to emphasize the importance of individualized treatment for patients.

Resolute, she launched ProgenaBiome, a genetic sequencing research company dedicated to understanding the gut flora at the clinical level to advance FMT and other microbial-based therapies. As her professional network grew, she realized that doctors and researchers worldwide were asking the same questions. She traveled, addressed medical forums, and wrote articles in her quest for answers. Meanwhile, she worked persistently to help patients with celiac disease, Crohn’s, ulcers, colitis, and other digestive ailments that she hypothesized were caused by dysbiosis in the gut.

Dr. Sabine Hazan’s quest continues. She and Dr. Borody believe that answers to many medical mysteries and the power to heal may be within the trillions of microbes in the gut flora. Answers are close.

Sheli Ellsworth

Science junkie Sheli Ellsworth grew up on a small farm in Texas and has seen both ends of the life cycle. She graduated magna cum laude from Texas Woman’s University and obtained her master’s degree from West Texas A&M with concentrations in psychology and biology.

After three cases of food poisoning, a son who licked the floor to gross out his sister, and a poop-eating pug—she too had questions about bacteria, behavior, and why she continues ordering chicken enchiladas.

A humorist at heart, this is her seventh book. If you enjoy Sheli’s writing, Confessions of a Pet Au Pair, an amusing guide to pet health is available on Amazon.

Thomas Borody

Microbiome pioneer Thomas Borody was born in Krakow, Poland. His father, Jan Borody, fought in the defense of Warsaw during the Nazi invasion of 1939, and then his parents then survived the German occupation of Poland. Jan, a pastor, worked as a double agent for the Polish underground while his photographer mother, Danuta, fed children trying to escape via sewage pipes from the ghetto.

His father found a way to take young Jewish girls out of ghettos and relocate them to the Krakow Carmelite nunnery where they could ultimately walk in groups over mountains to Switzerland and freedom. In Dec 1959, the family emigrated to Australia and settled in Sydney, where all three Borody children completed their Medical training. Edith became a family physician, Ian an obstetrician/ gynecologist, and Tom a gastroenterologist.

He completed his BS and MB BS degrees at the University of New South Wales then received his MD from Garvan Institute of Medical Research and University of Sydney School of Veterinary Science. He gained experience in parasitology, the treatment of TB and leprosy in the Solomon Islands then spent three years in clinical research at the Mayo Clinic, Rochester, MN. Later he earned a PhD at the University of Newcastle and his DSc at University of Technology Sydney.

Dr. Borody’s clinical interests focus on the development of novel treatments including those of human gut microbiome using fecal microbiota transplantation (FMT) to treat C. difficile infection, colitis, irritable bowel syndrome as well as neurologic and autoimmune disorders. In 1984, Dr. Borody established the Centre for Digestive Diseases (CDD) in Sydney, Australia and has overseen its growth into an active clinical research institute with 69 employees and 12 physicians treating around 10,000 patients per year. To date, Dr. Borody’s clinic has completed some 35,000 FMT treatments. He refined FMT by developing lyophilized (freeze-dried) FMT capsules and has published more than 310 research papers and has filed over 170 patents. His first FMT in 1988 was carried out on a patient with colitis who remained symptom free.

In 1985, he developed the first effective triple antibiotic therapy for H. pylori, which had a profound impact on curing hundreds of patients. The medication, was sold in the US as Helidac.

He later licensed quadruple antibiotic therapy now marketed as Pylera. He also developed the next generation, FDA-approved treatment for resistant H. pylori, Talicia.

Dr. Borody has also developed a Crohn’s disease treatment now in pivotal trials, as well as colonoscopy bowel prep products Glycoprep, Glycoprep C, Moviprep, and a capsule prep licensed to Salix.

Future Borody therapies include asthma-reversing treatment and a product to treat coronary heart disease as chronic infection. He is currently focusing on the eradication of coronavirus using repurposed, combined anti-viral therapy.

The microbiome

fecal transplant

best microbiome book

the best book on fecal transplant

 

This will change healthcare and make us more aware of our gut microbiome

Dr. Sabine Hazan-Steinberg and the the microbiome

This data will change healthcare and make us more aware of our gut microbiome

Progenabiome, a physician-owned genetic sequencing laboratory, found cutting-edge data on Clostridium difficile (C.diff), a disease burdening 500,000+ Americans yearly. They will present a validated, verified, and reproduced C.diff Assay at The American College of Gastroenterology (ACG) 2019 Annual Scientific Meeting on Monday, Oct. 28, 2019 in San Antonio.

Progenabiome, a genetic sequencing laboratory of the gut flora. Leading the way into the FUTURE by understanding the microbiome NOW. The quest for a new healthcare revolution!
Progenabiome, a genetic sequencing laboratory of the gut flora. Leading the way into the FUTURE by understanding the microbiome NOW. The quest for a new healthcare revolution!

“This data will change healthcare and make us more aware of our gut microbiome,” said Dr. Sabine Hazan-Steinberg, CEO and Founder of Progenabiome. “2500 years later, we’re proving Hippocrates right…everything starts in the gut.”

Dr. Hazan, a Malibu-based gastroenterologist, has 20+ years experience leading clinical trials, many for C.diff. When trials failed, she used fecal microbiota transplant (FMT), following advice from friend Dr. Neil Stollman, gastroenterologist at UCSF and East Bay Center for Digestive Health. She also followed great work by Dr. Thomas Borody, FMT pioneer and Centre for Digestive Diseases founder. Success post-FMT for recurrent C.diff suggested the microbiome holds many answers.

Knowing the C.diff microbe has existed for 10 million years, she questioned why it now takes 50,000 lives annually.

Dr. Sydney Finegold, infectious disease specialist who researched Autism/microbiome for 50 years, recommended she acquire a next-generation sequencer. When he passed in 2018, his books went to Hazan, hoping she could continue his legacy.

In January, she joined pathologist Dr. Brad Barrows and scientific director Dr. Andreas Papoutsis to launch Progenabiome. Their first run found non-toxigenic C.diff in every sample, including those not diagnosed with the disease. Preliminary data shows the C.diff microbe is not transmitted hand-to-mouth as previously believed. It is already in the gut and becomes toxic when something ingested triggers it.

Progenabiome will present this groundbreaking discovery at ACG 2019 (Poster 1027 / Booth 1931) and the 7th Annual International C.diff Conference November 6-7, 2019 in St. Louis.

Progenabiome is investigating the role of the gut flora in various diseases through 11 studies overlooked by New England IRB. Progenabiome’s Mission: to better understand, prevent, and treat diseases by analyzing specific genetic codes of 40 trillion gut microbes. Dr. Hazan believes the art of Medicine lies in our ability to see outside the box and recognize that all microbes and humans are unique.

For more: progenabiome.com / Twitter / Facebook / LinkedIn

Contact: Stephanie Davis, marketing@progenabiome.com

Noisy Furnace? – Top 5 Fixes | Repair and Replace

In this episode of Repair and Replace, Vance shows you audio examples and solutions to the most common causes of a noisy furnace. If the furnace is too loud, or is making unusual noises when running then it could be an issue with the motor, motor bearings, belt or ducting. Buy furnace repair parts online: https://www.amresupply.com/catalog/65… Replace a Blower Fan Motor and Wheel: https://youtu.be/bCGLGXyBhNE Replace a Noisy Inducer Blower: https://youtu.be/EsJhfFMZWJA Replace a Noisy Furnace Belt: https://youtu.be/APqq4X_gjUU Watch more furnace repairs: https://www.youtube.com/playlist?list… This furnace troubleshooting guide is applicable to all furnace brands including: Carrier, Emerson, York, Goodman, Honeywell, Lennox, Trane, Rheem, Bryant, Coleman, Westinghouse, White Rogers, Nordyne, Honeywell, Kenmore, Frigidaire, Amana AMRE Supply provides homeowners, service contractors, and property management with the parts and knowledge needed to get the best performance out of any property. Stocking the largest selection of appliance parts, heating, plumbing, lighting, and janitorial supplies, AMRE ships almost anywhere in Canada within 24 – 48 hours. Expert help is available online, over the phone or in person at one of the many locations across Canada.

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Air Conditioner Maintenance: 8 Tips You Can Do Yourself

Air Conditioner Maintenance – 8 Tips You Can Do Yourself

Do you know how to maintain your air conditioner? Did you even know you were supposed to? The good news is air conditioner maintenance is super easy and in this video we’ll tell you the 8 Air Conditioner Maintenance tips you can do on your own to help keep your air conditioner running as smooth as possible all summer long. It’s just super bright out here, Come on… It’s OK, I live here. Just like rotating the tires and changing the oil in your car, air conditioner maintenance will help prolong the life of your air conditioner, help it run more efficiently and cool your home better. You know In real estate they say the most important thing is location, location, location…well, when it comes to your air conditioner the most important thing is air flow, air flow, air flow.

And that’s why 3 of our air conditioner maintenance tips are related around air flow. We’ve broken your system down into 3 major parts. The outdoor unit, the indoor unit, and the thermostat. I’ve got a list of helpful maintenance tips for all 3…I just have to find my list first. Oh, Thanks. Unless you plan on using your “bear” hands, here’s a list of tools you’ll need Garden Hose New Filter Level Thermometer Raincoat (Optional) Rope Swing (Optional) OK, Let’s head to the outdoor unit. Your system pulls air in through the coils, and blows it out the top. And if your coils are blocked it can severely decrease the efficiency of your unit.

There’s a couple things you can do. The first thing you should do is cut power to the unit, the preferred method is to flip off the breaker. If you don’t have a breaker, pull the disconnect. Next you want to clear the debris away from the unit. Two feet around is a good rule of thumb to make sure the leaves, debris and grass clippings are away from the unit. If you have bushes or shrubs you want to trim those back as well.

Take your garden hose and rinse off the coils. Reach what you can with the garden hose and spray from the inside out. Let the water flow down the coils for a while, until it looks like you’ve gotten all the dirt off. Then spray off the debris you see on the outside. The fins on the unit are very fragile, be careful that you don’t bend them over. See if the unit looks level, if it’s too far off center you may want to have a professional level it up. Check the electrical connections – make sure that there’s no exposed wires. Check the insulation around the lineset to make sure it’s still good. Now reconnect the power, careful when you slide the disconnect back into place, you shouldn’t have to force it. Now let’s go to the indoor unit, where your filters are. Start by cutting the power. Check the filters to make sure you can still see light through it.

When replacing the filter, be sure to pay attention to the direction that the air is flowing. Make sure that the arrow on the filter lines up with the direction that the air flows through your unit. Replace filters as often as needed, this can be different for each home. So be sure to check it at least once a month. If you have a humidifier, remember to turn it off in the summer. Pour some water down the drain line to make sure that it’s not clogged. Some people add a little bleach to the water to clean the line.

Ok, now we’re at the thermostat. Really the only thing you need to do to check and make sure it working properly is verify the temperature on the display matches the temperature in the room. An easy way to do that is to just get a visual read thermometer and make sure they match. As long as you’re within 3 degrees or so, you’ll be fine. These Air Conditioner Maintenance Tips that we’ve shared with you are things that anyone can do on their own. But manufacturers actually recommend that you take it one step further. In the owner’s manual it actually says that you should have your system inspected regularly by a properly trained technician. So, as part of your Air Conditioner’s Maintenance, once a year, you should have a Certified HVAC technician come out and tune-up and inspect your unit. They’ll have the specialty tools and gauges to go more indepth.

They’ll check voltages, check the capacitor, see if there’s any obvious concerns, check the refrigerant levels, those hard to reach components and more. They should review their findings with you and answer any questions that you have. If you have a friend or neighbor that works on Air Conditioners, you might be able to get them to do this for you but if you don’t know anyone…in your local market you should be able to find a certified HVAC Contractor to come to your home and perform this annual service.

If you’re in the Utah market, give Any Hour Services a call. They’ll send a certified HVAC technician to your home to perform a 23 point Air Conditioner Tune-Up. Call 801-503-0130 If you’ve found this air conditioner maintenance video helpful and entertaining, give us a thumbs up. If there’s other stuff you want to know about how your electrical, plumbing, heating or air conditioning system works in your home, leave your suggestions in the comments below.

Don’t forget to subscribe so you can get notification when the new videos come out. Have a great day and thanks for watching! .

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HVAC Edmonton

How to Find the Best Camera Angles

Free Guide! How to find the best camera angles for dialogue scenes: https://wolfcrow.ontraport.com/tl/7 Camera guides, filmmaking and cinematography courses: http://wolfcrow.ontraport.com/tl/8 What’s in my camera bag: http://wolfcrow.ontraport.com/tl/9 Find gear on Amazon: https://www.amazon.com/shop/wolfcrow/ Find gear on B&H: https://bhpho.to/2N3Na21 Watch “Fight Night”: https://youtu.be/CvL75ILHkDo If you want the seven most practical tips to finding the best camera angles, then watch this video. I’ve condensed everything I’ve learned over the last few years making camera analysis videos into this one video; let’s call it the 10-step formula to finding the best camera angles. Your secret weapon, something you can actually use for your film. Download and store on your mobile phone to use any time! Links can be to our affiliates and we might get paid a commission for any purchases you make. Please support wolfcrow and purchase using these links. It won’t cost you extra. Don’t forget to subscribe!

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Cinematography Edmonton

Real Estate/listing/Edmonton/Webber-Greens/e4168755-9423-209-street-edmonton-ab-t5t-7j5/

Real EstatelistingEdmontonWebber-Greense4168755-9423-209-street-edmonton-ab-t5t-7j5

Edmonton Real Estate 9423 209 Street, Webber Greens, Edmonton, T5T 7J5

 

3 Beds3 Baths$379,900

1,473 SQ. FeetBuilt In 2018Lot Size: 3,049 sqft

Single FamilyMLS #E4168755

 

This Rundle duplex in Webber Greens features 3 bedrooms, 2.5 baths + a double attached garage PLUS a Side Entrance! The main floor features a functional and sleek and modern kitchen with full height upper cabinets, stainless appliances, tile backsplash, pantry, and plenty of granite counter space. Open to the dining area and living room for true entertainment functionality. Rounding out the main floor is a large front entry with and half bath, coat closet, and mud room. Upstairs the master bedroom is the perfect place to escape, with a large walk-in closet, plenty of natural light from the large windows off the front of the home, and a 4 piece ensuite. 2 additional bedrooms with ample space for kids, office or guest room, a full 4 piece bath, laundry area and linen closet complete the upper level. The basement is ready for income suite development. This property will be fully landscaped and has everything you need, steps to schools, parks, shopping, WEM, Costco, Henday, Whitemud, and all amenities.

Essential Information

  • MLS® #E4168755
  • Price$379,900
  • Bedrooms3
  • Bedrooms Above Grade3
  • Bathrooms3.00
  • Full Baths2
  • Half Baths1
  • Has EnsuiteY
  • Square Footage1,473
  • Acres0.07
  • Year Built2018
  • Property TypeSingle Family
  • Building TypeHalf Duplex
  • Style2 Storey

Interior

  • FlooringCarpet, Laminate Flooring
  • Goods IncludedDishwasher-Built-In, Dryer, Garage Control, Garage Opener, Microwave Hood Cover, Refrigerator, Stove-Electric, Washer
  • HeatingForced Air-1
  • Has BasementYes
  • BasementFull, Unfinished
  • # of Stories2

Community Information

  • Address9423 209 Street
  • AreaEdmonton
  • CommunityWebber Greens
  • CityEdmonton
  • CountyALBERTA
  • ProvinceAB
  • Postal CodeT5T 7J5

Exterior

  • ExteriorStone, Vinyl
  • RoofAsphalt Shingles
  • ConstructionWood Frame
  • FoundationConcrete

Amenities

  • FeaturesNo Animal Home, No Smoking Home
  • Exterior FeaturesCul-De-Sac, Flat Site, Golf Nearby, Landscaped, Low Maintenance Landscape, No Back Lane, No Through Road, Playground Nearby, Public Transportation, Schools, Shopping Nearby, Not Fenced
  • ParkingDouble Garage Attached
  • # Garage Parking Spaces2
  • Garages19W X 23D

School Information

  • ElementaryWINTERBURN SCHOOL
  • MiddleMICHAEL PHAIR SCHOOL
  • HighJASPER PLACE SCHOOL

Additional Information

  • HOA Fees200.00
  • HOA Fees Freq.Annually
  • Lot ShapeRectangular
  • Front ExposureWest

Map, Directions & Schools

Yellow Ferrari 488 Racing Car wrapped Matte White – the HARDEST wrap!

 

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Young Steve Jobs on how to hire, manage, and lead people – MUST WATCH

Check out these books about Steve Jobs: * Steve Jobs: https://amzn.to/2PGH3nM * The Presentation Secrets of Steve Jobs: https://amzn.to/2JB1j55 * Becoming Steve Jobs: https://amzn.to/2QgZKf8 * Steve Jobs: The Man Who Thought Differently: https://amzn.to/2AHIqdQ * Steve Jobs (Movie): https://amzn.to/2CZgLq3 How Steve Jobs managed people, led people, gave people a common vision, hired insanely great people, and how he avoided “professionals.” * Join my BELIEVE newsletter: http://www.evancarmichael.com/newslet…

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Why we have too few women leaders | Sheryl Sandberg

Why we have too few women leaders

http://www.ted.com Facebook COO Sheryl Sandberg looks at why a smaller percentage of women than men reach the top of their professions — and offers 3 powerful pieces of advice to women aiming for the C-suite. TEDTalks is a daily video podcast of the best talks and performances from the TED Conference, where the world’s leading thinkers and doers give the talk of their lives in 18 minutes. TED stands for Technology, Entertainment, Design, and TEDTalks cover these topics as well as science, business, development and the arts. Closed captions and translated subtitles in a variety of languages are now available on TED.com, at http://www.ted.com/translate. Watch a highlight reel of the Top 10 TEDTalks at http://www.ted.com/index.php/talks/top10

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How To Find A Mentor – Boss In The Bentley

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The Role of a Mentor

Mentors can serve several different roles in helping you learn the essentials more quickly. In some cases, providing a quick tip can be solid gold in becoming proficient or knowledgeable about an activity; and that information might have taken much longer to acquire on your own. In other situations, a mentor might feed you a constant stream of support and encouragement to help keep you on track. Without directing you, a mentor can simply offer guidance that will help keep you on the right path to avoid career pitfalls which might derail your drive to success.

Mentors also serve in the role of a sounding board, willing to listen and to offer their own recommendations to you. This can be far more important than it sounds, yet quite often in life, all you really need is to get something off your chest and relate it to a sympathetic colleague. Their feedback and encouragement will be enough to keep you going, striving to achieve your objectives. A caring mentor who is genuinely interested in advancing your career can show you how everything you learn on this job can be put to use somehow on your next one — in other words, how to extract the greatest value from all your experiences.

If a mentor has done a good job of guiding you, you will have learned some of the most important lessons for your career and for your life. This learning will then put you in a much better position to become a leader yourself, when the time comes. What you’ve learned along the way can become immensely useful in helping you guide the lives and careers of others, and you will be armed with the knowledge you need to earn ever increasing responsibility and create greater success.

Read full article here ——->  6+ Reasons Sales Leaders in Biotech and Diagnostics Need Mentors